Biomarker and target discovery of type II diabetes in small animals

Starting with a limited set of samples and metadata for training (diseased versus control animals), a phenotype of type II diabetes was defined and led to the discovery of potential new biomarkers and therapeutic targets for the disease. 

  • Whole blood from C57BL/6 mice – 2uL volume
  • 100% specificity and 100% sensitivity on sample classification using Probius signature and biomarker network
  • A posteriori analysis of disease pathways involving immune response and glucose and fatty acid metabolism

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