Case study

Screening of tuberculosis and associated co-morbidities

In this study, patient samples were used to train and validate a screening algorithm for quick detection of tuberculosis infection in plasma for early screening ( no need to sample low abundance micro-bacterium)

• Human plasma samples from 3 different clinical sites in South Africa

• 90% sensitivity and 90% specificity, exceeding WHO recommendation

• 30 min from sample to information, using simple workflow compatible with patient triaging in underserved communities

• A posteriori repurposing of training data to screen for co-morbidities (HIV)

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